Weight loss
surgery, or bariatric surgery, may not just help you shed the pounds in
the short-term – it may actually affect your body’s collection of
microbes and help stave off obesity in the long-term.
That’s
according to research that investigated the effects of weight loss surgery
after almost a decade. The team from the University of Gothenburg in Sweden
studied 14 women who had undergone two forms of surgery nine years previously, Roux-en-Y gastric
bypass and vertical banded gastroplasty. Both were found to alter the
body’s micro biome.
In the
research, published in the journal Cell Metabolism, microbes from the
stool samples of women who underwent these surgeries were transplanted into
specially bred “germ-free” mice that were devoid of any gut bacteria. Microbes
from a separate group of obese women who had not undergone bariatric
surgery were also transplanted into similar mice via the same method.
It was found
that those mice given the microbes from the women who had surgery gained less
weight than the other mice. While both gained weight following the transplant,
the mice given the post-surgery microbes from Roux-en-Y and vertical banded
gastroplasty patients gained 43% and 26% less fat respectively than the
control group. This may have been due to the slimmer mice burning fewer
carbohydrates and more fat than the control group, but the exact microbes
at play are not yet known.
"Our
findings are important in light of the growing epidemic of obesity and
associated diseases," said Fredrik Bäckhed of the University of
Gothenburg, who led the research, in a statement. "Since surgery always
confers a risk, it is critical to identify non-surgical strategies. One
potential strategy would be to devise novel probiotics based on our findings
that can be supplied to obese individuals."
The findings
suggest that the success of bariatric surgery – which includes reducing the
size of a stomach with a gastric band or removing part of the stomach – may in
part be due to this lesser-known microbiome effect, rather than just the
surgery itself. This means that, in future, it might be easier and more
beneficial to treat obesity by transplanting these weight-loss-associated
microbes, rather than performing the complicated, expensive and
occasionally risky procedures.
The problem
now will be to work out which of the 1,000 types of microbes in our intestines
are actually responsible for this apparent effect. If that can be narrowed
down, it could have huge implications for treating obesity in future.
This post was
originally published here: Weight
Loss Surgery May Alter Gut Microbes To Help Keep Fighting Obesity
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An Abundance Of Fresh Produce To Lose Weight Naturally
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